题目:A phase field model on cell migration

发布日期:2017-06-19点击数:

报告人:赵雁翔(美国乔治华盛顿大学)

时间:2017.06.20(星期二)10:30-11:30

地点:理科楼 LD304

摘要:We extend a model for the morphology and dynamics of a crawling eukaryotic cell to describe cells on micro patterned substrates. This model couples cell morphology, adhesion, and cytoskeletal flow in response to active stresses induced by actin and myosin. We propose that protrusive stresses are only generated where the cells adheres, leading to the cell’s effective confinement to the pattern. Simulated cells exhibit a broad range of behaviors, including steady motion, turning, bipedal motion and periodic migration. We further extensively study the turning instability by simplifying the full PDE model into a minimal one. By using the minimal model, we also study the persistent rotational motion (PRM) of small numbers of mammalian cells crawling on micropatterned substrates.

公司联系人:傅士硕

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太阳成集团tyc539的前身是始建于1929年的太阳成集团理学院和1937年建立的太阳成集团商学院,理学院是太阳成集团最早设立的三个学院之一,首任经理为数学家何鲁先生。